2,811 research outputs found

    Trends in Americans food-related time use: 1975-2006

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    Journal ArticleObjective: To describe how the time spent in food-related activities by Americans has changed over the past 30 years. Design: Data from four national time diary surveys, spanning 1975-2006, are used to construct estimates of trends in American adults' time spent in food-related activities. Multivariate Tobits assess how food-related activities have changed over time controlling for sociodemographic and economic covariates. Results: Both bivariate and multivariate estimates reveal that between 1975 and 2006, American women's time spent in food preparation declined substantially, whereas the time spent in these activities by American men changed very little. On the contrary, grocery shopping time increased modestly for both men and women. The primary eating time (i.e. time when eating/drinking was the respondent's main focus) declined for both men and women over this historical period, and the composition of this time changed with less primary eating time being done alone. Concurrently, secondary eating time (i.e. time when something else had the respondent's primary attention, but eating/drinking simultaneously occurred) rose precipitously for both women and men between 1975 and 1998. Conclusions: The total time spent in eating (i.e. primary plus secondary eating time) has increased over the past 30 years, and the composition of this time has shifted from situations in which energy intake can be easily monitored to those in which energy intake may be more difficult to gauge. Less time is also being spent in food preparation and clean-up activities. Future research should explore possible links between these trends and Americans' growing obesity risk

    Delirium in the ICU: time to probe the hard questions

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    Prevalent in critically ill patients, delirium remains poorly understood and difficult to treat. In a cross-sectional study conducted in 12 countries, delirium was identified in close to one third of patients and was independently associated with increased mortality. While such epidemiological accounts represent an important cornerstone for research, scientific efforts are needed to elucidate the causes of delirium and the mechanisms underlying its association with poor outcomes

    Time use choices and healthy body weight: A multivariate analysis of data from the American Time use Survey

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    <p>Abstract</p> <p>Background</p> <p>We examine the relationship between time use choices and healthy body weight as measured by survey respondents' body mass index (BMI). Using data from the 2006 and 2007 American Time Use Surveys, we expand upon earlier research by including more detailed measures of time spent eating as well as measures of physical activity time and sedentary time. We also estimate three alternative models that relate time use to BMI.</p> <p>Results</p> <p>Our results suggest that time use and BMI are simultaneously determined. The preferred empirical model reveals evidence of an inverse relationship between time spent eating and BMI for women and men. In contrast, time spent drinking beverages while simultaneously doing other things and time spent watching television/videos are positively linked to BMI. For women only, time spent in food preparation and clean-up is inversely related to BMI while for men only, time spent sleeping is inversely related to BMI. Models that include grocery prices, opportunity costs of time, and nonwage income reveal that as these economic variables increase, BMI declines.</p> <p>Conclusions</p> <p>In this large, nationally representative data set, our analyses that correct for time use endogeneity reveal that the Americans' time use decisions have implications for their BMI. The analyses suggest that both eating time and context (i.e., while doing other tasks simultaneously) matters as does time spent in food preparation, and time spent in sedentary activities. Reduced form models suggest that shifts in grocery prices, opportunity costs of time, and nonwage income may be contributing to alterations in time use patterns and food choices that have implications for BMI.</p

    Septic-associated encephalopathy - everything starts at a microlevel

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    Sepsis-associated encephalopathy is associated with increased mortality and morbidity. Its pathophysiology remains insufficiently elucidated, although there is evidence for a neuroinflammatory process sequentially involving endothelial activation, blood-brain barrier alteration and cellular dysfunction and alteration in neurotransmission. Experimental studies have shown that microcirculatory dysfunction, a consequence of endothelial activation, is an early pathogenic step. To date, we do not know whether it is present in septic patients, whether it accounts for clinical features and whether it is treatable

    Weakness in the ICU: a call to action

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    Muscle weakness is prevalent in critically ill patients and can have a dramatic effect on short- and long-term outcomes, yet there are currently no interventions with proven efficacy in preventing or treating this complication. In a new randomized trial, researchers found that serial electrical muscle stimulation significantly mitigated ultrasound-defined muscle atrophy, and the treatment was not linked to adverse effects. Although preliminary, these results, together with other recent studies, indicate a paradigm shift to a proactive approach in managing neuromuscular complications in the ICU

    Methodology capture: discriminating between the "best" and the rest of community practice

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    <p>Abstract</p> <p>Background</p> <p>The methodologies we use both enable and help define our research. However, as experimental complexity has increased the choice of appropriate methodologies has become an increasingly difficult task. This makes it difficult to keep track of available bioinformatics software, let alone the most suitable protocols in a specific research area. To remedy this we present an approach for capturing methodology from literature in order to identify and, thus, define best practice within a field.</p> <p>Results</p> <p>Our approach is to implement data extraction techniques on the full-text of scientific articles to obtain the set of experimental protocols used by an entire scientific discipline, molecular phylogenetics. Our methodology for identifying methodologies could in principle be applied to any scientific discipline, whether or not computer-based. We find a number of issues related to the nature of best practice, as opposed to community practice. We find that there is much heterogeneity in the use of molecular phylogenetic methods and software, some of which is related to poor specification of protocols. We also find that phylogenetic practice exhibits field-specific tendencies that have increased through time, despite the generic nature of the available software. We used the practice of highly published and widely collaborative researchers ("expert" researchers) to analyse the influence of authority on community practice. We find expert authors exhibit patterns of practice common to their field and therefore act as useful field-specific practice indicators.</p> <p>Conclusion</p> <p>We have identified a structured community of phylogenetic researchers performing analyses that are customary in their own local community and significantly different from those in other areas. Best practice information can help to bridge such subtle differences by increasing communication of protocols to a wider audience. We propose that the practice of expert authors from the field of evolutionary biology is the closest to contemporary best practice in phylogenetic experimental design. Capturing best practice is, however, a complex task and should also acknowledge the differences between fields such as the specific context of the analysis.</p

    New sustainable ternary copper phosphide thermoelectrics

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    Funding: R. J. Q. and J.-W. G. B. acknowledge the Leverhulme Trust (RPG-2020-177). A. D. H. acknowledges the EPSRC (EP/ R013004/1).The thermoelectric performance of ACuP (A = Mg and Ca) with abundant elements and low gravimetric density is reported. Both systems are p-type doped by intrinsic Cu vacancy defects, have large power factors and promising figures of merit, reaching zT = 0.5 at 800 K. This demonstrates that copper phosphides are a potential new class of thermoelectric materials for waste heat harvesting.Publisher PDFPeer reviewe

    Emergency Neurological Life Support: Intracranial Hypertension and Herniation

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    Sustained intracranial hypertension and acute brain herniation are “brain codes,” signifying catastrophic neurological events that require immediate recognition and treatment to prevent irreversible injury and death. As in cardiac arrest, a brain code mandates the organized implementation of a stepwise management algorithm. The goal of this emergency neurological life support protocol is to implement an evidence-based, standardized approach to the evaluation and management of patients with intracranial hypertension and/or herniation
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